Alpha-fetoprotein inhibits autophagy to promote malignant behaviour in hepatocellular carcinoma cells by activating PI3K/AKT/mTOR signalling

Shanshan Wang; Mingyue Zhu; Qiaoyun Wang; Yuli Hou; Lei Li

doi:10.1038/s41419-018-1036-5

Alpha-fetoprotein inhibits autophagy to promote malignant behaviour in hepatocellular carcinoma cells by activating PI3K/AKT/mTOR signalling

Shanshan Wang, Mingyue Zhu, Qiaoyun Wang, Yuli Hou, Lei Li, Honglei Weng, Yan Zhao, Dexi Chen, Huiguo Ding, Junli Guo, Mengsen Li

Springer Nature (2018) • Volume 9, Issue 10, Pages 1027-1027

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Publication Info

DOI

10.1038/s41419-018-1036-5

Language

English

Topic

Autophagy in Disease and Therapy

Keywords

PI3K/AKT/mTOR pathway, Autophagy, Protein kinase B, Cell growth, Cancer research, Apoptosis, PTEN, Biology, Flow cytometry, RPTOR, Cell biology, Chemistry, Molecular biology, Signal transduction, Biochemistry

Published

October 9, 2018

Citations

116 citations

FWCI

12.83

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Alpha-fetoprotein inhibits autophagy to promote malignant behaviour in hepatocellular carcinoma cells by activating PI3K/AKT/mTOR signalling

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