Disease-Specific as Well as Generic Quality of Life Is Widely Impacted in Autoimmune Hypothyroidism and Improves during the First Six Months of Levothyroxine Therapy
Kristian Hillert Winther, Per Karkov Cramon, Torquil Watt, Jakob Bue Bjørner, Ola Ekholm, Ulla Feldt‐Rasmussen, Mogens Grøenvold, Åse Krogh Rasmussen, László Hegedüs, Steen Joop Bonnema
Public Library of Science (2016) • Volume 11, Issue 6, Pages e0156925-e0156925
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Abstract
In this population of hypothyroid patients, HRQL was widely affected before treatment, with tiredness as the cardinal impairment according to both ThyPRO and SF-36. Many aspects of HRQL improved during the first six months of LT4 therapy, but full recovery was not obtained. Our results may help clinicians inform patients about expected clinical treatment effects.