The Effects of Influenza Vaccination of Health Care Workers in Nursing Homes: Insights from a Mathematical Model

Carline van den Dool; Marc J. M. Bonten; Eelko Hak; Janneke C. M. Heijne; Jacco Wallinga

doi:10.1371/journal.pmed.0050200

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The Effects of Influenza Vaccination of Health Care Workers in Nursing Homes: Insights from a Mathematical Model

Carline van den Dool, Marc J. M. Bonten, Eelko Hak, Janneke C. M. Heijne, Jacco Wallinga

Public Library of Science (2008) • Volume 5, Issue 10, Pages e200-e200

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Abstract

The absence of herd immunity in nursing homes implies that vaccination of every additional HCW protects an additional fraction of patients. Because of large stochastic variations, results of small-sized clinical trials on the effects of HCW vaccination should be interpreted with great care. Moreover, the large variations in attack rates should be taken into account when designing future studies.

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Publication Info

DOI

10.1371/journal.pmed.0050200

Language

English

Topic

Influenza Virus Research Studies

Keywords

Vaccination, Herd immunity, Medicine, Outbreak, Health care, Transmission (telecommunications), Influenza A virus, Environmental health, Immunity, Infection control, Influenza vaccine, Nursing homes, Virus, Emergency medicine, Immunology, Intensive care medicine, Virology, Nursing, Immune system

Published

October 24, 2008

Citations

123 citations

FWCI

7.39

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The Effects of Influenza Vaccination of Health Care Workers in Nursing Homes: Insights from a Mathematical Model

Abstract

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Publication Info

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