Induction of multiple pleiotropic drug resistance genes in yeast engineered to produce an increased level of anti-malarial drug precursor, artemisinic acid

Dae‐Kyun Ro; Mario Ouellet; Eric M. Paradise; Helcio Burd; Diana G. Eng

doi:10.1186/1472-6750-8-83

Induction of multiple pleiotropic drug resistance genes in yeast engineered to produce an increased level of anti-malarial drug precursor, artemisinic acid

Dae‐Kyun Ro, Mario Ouellet, Eric M. Paradise, Helcio Burd, Diana G. Eng, Christopher J. Paddon, Jack D. Newman, Jay D. Keasling

BioMed Central (2008) • Volume 8, Issue 1, Pages 83-83

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Publication Info

DOI

10.1186/1472-6750-8-83

Language

English

Topic

Plant biochemistry and biosynthesis

Keywords

Biology, Artemisinin, Artemisia annua, Plasmid, Biochemistry, Yeast, Plasmodium falciparum, Sesquiterpene lactone, Gene, Sesquiterpene, Botany, Malaria

Published

November 4, 2008

Citations

193 citations

FWCI

4.65

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Induction of multiple pleiotropic drug resistance genes in yeast engineered to produce an increased level of anti-malarial drug precursor, artemisinic acid

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Publication Info

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