Inhibition of Amino Acid Metabolism Selectively Targets Human Leukemia Stem Cells

Courtney L. Jones; Brett M. Stevens; Angelo D’Alessandro; Julie A. Reisz; Rachel Culp‐Hill

doi:10.1016/j.ccell.2018.10.005

Inhibition of Amino Acid Metabolism Selectively Targets Human Leukemia Stem Cells

Courtney L. Jones, Brett M. Stevens, Angelo D’Alessandro, Julie A. Reisz, Rachel Culp‐Hill, Travis Nemkov, Shanshan Pei, Nabilah Khan, Biniam Adane, Haobin Ye, Anna Krug, Dominik Reinhold, Clayton A. Smith, James DeGregori, Daniel A. Pollyea...

Cell Press (2018) • Volume 34, Issue 5, Pages 724-740.e4

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Publication Info

DOI

10.1016/j.ccell.2018.10.005

Language

English

Topic

Acute Myeloid Leukemia Research

Keywords

Myeloid leukemia, Metabolism, Oxidative phosphorylation, Amino acid, Catabolism, Metabolome, Stem cell, Leukemia, Biology, Biochemistry, Population, Cancer research, Cell biology, Medicine, Immunology, Metabolite

Published

November 1, 2018

Citations

528 citations

FWCI

42.06

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Inhibition of Amino Acid Metabolism Selectively Targets Human Leukemia Stem Cells

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Publication Info

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