Efficient measurement and factorization of high-order drug interactions in<i>Mycobacterium tuberculosis</i>

Murat Cokol; Nurdan Kuru; Ece Bicak; Jonah Larkins‐Ford; Bree B. Aldridge

doi:10.1126/sciadv.1701881

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Efficient measurement and factorization of high-order drug interactions in<i>Mycobacterium tuberculosis</i>

Murat Cokol, Nurdan Kuru, Ece Bicak, Jonah Larkins‐Ford, Bree B. Aldridge

American Association for the Advancement of Science (2017) • Volume 3, Issue 10, Pages e1701881-e1701881

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Abstract

Geometrically optimized sampling of drug-dose combinations enables systematic identification of high-order drug synergies.

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Publication Info

DOI

10.1126/sciadv.1701881

Language

English

Topic

Tuberculosis Research and Epidemiology

Keywords

Drug, Mycobacterium tuberculosis, Computational biology, Sampling (signal processing), Tuberculosis, Identification (biology), Factorization, Computer science, Order (exchange), Medicine, Biology, Pharmacology, Algorithm, Pathology, Business, Ecology

Published

October 6, 2017

Citations

146 citations

FWCI

9.52

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Efficient measurement and factorization of high-order drug interactions in<i>Mycobacterium tuberculosis</i>

Abstract

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Publication Info

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